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Professor
Areas of Interest: Dosage forms, drug delivery, pharmacokinetics, compounding, and contract formulation lab services
Fang Zhao
Education:

Ph.D., University of Kansas
M.S., University of Kansas
B.A., University of Kansas

Teaching

  • PHAR 3122 - Pharmacy Calculations
  • PHAR 3242 - Pharmaceutics
  • PHAR 4112 - Applied Pharmaceutics
  • PHAR 5514 - Topics in Drug Delivery
  • CHEM 414 - Pharmaceutics

Research and Scholarship Interest

  • Extemporaneous compounding (sterile and non-sterile) and stability evaluation
  • Development and evaluation of oral, ophthalmic and parenteral formulations
  • Characterization of physicochemical properties of drugs and excipients
  • Teaching innovations in pharmaceutical sciences

Recent Grants and Contracts

  • $23,385 contract (co-investigator) from Iuvo Biosciences, Rush-Henrietta, New York. Re-formulation of an ophthalmic drug product to support a 505(b)(2) NDA. Jul 2019 - present.
  • $6,800 contract (co-investigator) from Iuvo Biosciences, Rush-Henrietta, New York. Formulation of an oral drug candidate and evaluation in simulated GI fluids. Jul 2019 - present.
  • $4,468 faculty development grant (co-investigator) from St. John Fisher College. Compounded pimavanserin suspensions for enteral feeding tubes. Jun 2019 – May 2020.
  • $2,500 Faculty Research Award Program grant (co-investigator) from Wegmans School of Pharmacy, St. John Fisher College, Rochester, NY. Evaluation of shelf life extension of oseltamivir. Jul 2019 – Jun 2020.
  • $19,791 contract (co-investigator) from Iuvo Biosciences, Rush-Henrietta, New York. Pre-formulation and formulation studies of a small molecule oral drug candidate. Jun – Dec 2019.
  • $5,000 contract (co-investigator) from Iuvo Biosciences, Rush-Henrietta, New York. Formulation development of a drug candidate to support clinical studies. Mar – Jun 2019.
  • $1,800 Faculty Research Award Program grant from Wegmans School of Pharmacy, John Fisher College, Rochester, NY. Physical-chemical stability of compounded sildenafil 100 mg orally dissolving tablets. Jul 2018 – present.
  • $5,000 contract from University of Rochester Medical Center, Rochester, New IV formulation development of poorly water soluble drugs. Mar 2018 – present.
  • $18,454 Investigator Initiated Study Grant from Sunovion Pharmaceuticals Inc., Marlborough, MA. Formulation and stability study of eslicarbazepine acetate oral suspensions. Jan – Sep 2018.
  • $2,471 Faculty Research Award Program grant from Wegmans School of Pharmacy, St. John Fisher College. The study of Suboxone dosing: assessing medication content uniformity and stability. Jul 2017 – present.

Recent Journal Publications

  • Uttaro E, Zhao F, and Schweighardt A. Filling the gaps on the ISMP Do Not Crush list for immediaterelease products. Accepted by Int. J. Pharm. Compd.
  • Cheung M, Zhao F, and Dave V. Physical-chemical stability of compounded sildenafil 100-mg rapiddissolving tablets. Int. J. Pharm. Compd. 25:82-87 (2021).
  • Uttaro E, Pudipeddi M, Schweighardt A, and Zhao F. To crush or not to crush – a brief review of novel tablets and capsules prepared from nanocrystal and amorphous solid dispersion technologies. J. Health Syst. Pharm. Accepted for publication.
  • Cheung M, Zhao F, and Dave V. Physical-chemical stability of compounded sildenafil 100 mg rapid dissolving tablets (RDTs). J. Pharm. Comp. Accepted for publication.
  • Buga I, Uzoma J, Reindel K, Rashid K, Diep T, McCartan P, and Zhao F. Physical and chemical stability of dexamethasone sodium phosphate in intravenous admixtures used to prevent chemotherapy-induced nausea and vomiting. Pharm. First published online: November 15, 2019. https://doi.org/10.1177/0018578719888912
  • Sabins D, Diep T, McCartan P, Patel S, and Zhao F. Stability and compatibility of diphenhydramine hydrochloride in intravenous admixture: a new look at an old drug. Hosp. Pharm. 54:330-334 (2019) . https://doi.org/10.1177/0018578718802586
  • Reindel KL, DeAngelis MJ, Ferrara AS, Conn KM, Phillips EM, Corigliano AT, and Zhao F. An exploratory study of Suboxone (buprenorphine/naloxone) film splitting: cutting methods, content uniformity, and stability. J. Pharm. Compd. 23:258-263 (2019).
  • Kimaru IW, Corigliano AT and Zhao Using classical EDTA titrations to measure calcium and magnesium in intravenous fluid bags. J. Chem. Educ. First published Nov 12, 2018. 10.1021/acs.jchemed.8b00412
  • Cutaia K, Chablani L, and Zhao Vehicles for compounded oral liquid medications: A Review. Int. J. Pharm. Compd. 22:480-489 (2018).
  • Zhao F, Dave VS, Mar MZ, and Perri Formulation and stability study of eslicarbazepine acetate oral suspensions for extemporaneous compounding. Int. J. Pharm. Compd. 22:433-439 (2018).
  • Sabins D, Diep T, McCartan P, Patel S, and Zhao Stability and compatibility of diphenhydramine hydrochloride in intravenous admixture: a new look at an old drug. Hosp. Pharm. First published Sep 22, 2018. https://doi.org/10.1177/0018578718802586
  • Camp N, Nadra J, Hughes S, Gilbert J, and Zhao Stability of extemporaneously prepared ophthalmic solutions for mydriasis. Am. J. Health Syst. Pharm. 75:e231-e235 (2018). https://doi.org/10.2146/ajhp161068
  • M DeAngelis, A Ferrara, K Gregory, K Zammit, and F Zhao. Stability of 2 mg/mL Adenosine Solution in Polyvinyl Chloride and Polyolefin Infusion Bags. Hosp. Pharm. Pre-published Nov 30, 2017. http://journals.sagepub.com/doi/10.1177/0018578717742516
  • K Reindel, F Zhao, S Hughes, and V Dave. In vitro evaluation of eslicarbazepine delivery via enteral feeding tubes. Hosp. Pharm. 52:752-760 (2017). http://journals.sagepub.com/doi/10.1177/0018578717732340
  • S Rush, C Vernak, and F Zhao. A pilot stability study of dehydroepiandrosterone (DHEA) rapid-dissolving tablets prepared by extemporaneous compounding. Int. J. Pharm. Compd. 21:83-87 (2017). https://www.ijpc.com/Abstracts/Abstract.cfm?ABS=4277
  • M Caraballo, S Donmez, K Nathan, and F Zhao. Compounded apixaban suspensions for enteral feeding tubes. Hosp. Pharm. 52:478-482 (2017). https://doi.org/10.1177/0018578717720507

Patents

  • F Zhao. Packaging solutions. US Patent No. US 9,527,617. Date of Patent: Dec 27, 2016.
  • F Zhao, V Barniak, M Coffey, and R Braun. Packaging solutions. US Patent No. 8,490,782 B2. Date of Patent: Jul 23, 2013.
  • S Burke, E Phillips, F Zhao, V Barniak, and J Salamone. Ophthalmic compositions comprising a branched, glycerol monoalkyl compound and a fatty acid monoester. US Patent No. 7,670,997 B2. Date of Patent: Mar 2, 2010

Recent Poster Presentations

  • DelMonte K, Camenisch T, Zhao F. Shelf-life stability of expired Tamiflu. AACP (American Association of Colleges of Pharmacy) Annual Meeting. Jul 2021.
  • Uttaro E, Zhao F, and Schweighardt A. Filling in the gaps on the ISMP Do Not Crush List. 2020 ASHP (American Society of Health-system Pharmacists) Midyear Clinical Meeting. Dec 2020.
  • Buga I, Uzoma J, Reindel K, Rashid E, Diep T, McCartan P, and Zhao F. Striving for stability: an evaluation of stability and compatibility of dexamethasone sodium phosphate in IV admixtures used for prevention of chemotherapy-induced nausea and vomiting. 2019 ASHP (American Society of Health-system Pharmacists) Midyear Clinical Meeting. Dec 2019.
  • Buga I, Uzoma J, Reindel K, Rashid K, Diep T, McCartan P, and Zhao F. Stability is Everything: An Analysis of Dexamethasone Sodium Phosphate in IV Admixtures. PSSNY (Pharmacists Society of the State of New York) 2019 Mid-winter Meeting. Jan 2019.
  • Reindel K, Zhao F, Phillips E, Conn K, and Corigliano A. Exploratory study of content uniformity and stability of split buprenorphine/naloxone films. ASHP (American Society of Health-system Pharmacists) 53th Midyear Clinical Meeting. Dec 2018
  • Dave VS, Zhao F, Mar MZ, and Perri JR. Formulation and stability study of eslicarbazepine acetate oral suspensions. AACP (American Association of Colleges of Pharmacy) Annual Meeting. Jul 2018.
  • DeAngelis M, Ferrara A, Conn K, Phillips E, and Zhao F. Assessment of splitting methods for buprenorphine/naloxone sublingual films. NYSCHP (New York State Council of Health-system Pharmacists) 57th Annual Assembly. Apr 2018.
  • Kimaru I, Corigliano A, Chichester K, and Zhao F. Measuring calcium and magnesium levels in IV fluids: a real life application for the undergraduate analytical chemistry laboratory. PITTCON/ACS Division of Analytical Chemistry Poster Session. Feb 2018.
  • Reindel K, Zhao F, Hughes S, and Dave V. In vitro evaluation of eslicarbazepine delivery via enteral feeding tubes. ASHP (American Society of Health-system Pharmacists) 52th Midyear Clinical Meeting. Dec 2017

Additional Information