Assistant Professor
Areas of Interest: Microfluidics, nanoparticles, 3D bioprinting, and remote sensing of microbial populations.
Fernando Ontiveros-Llamas
Education:

Ph.D., M.S., University of Rochester
B.S., National Autonomous University of Mexico

Teaching

PETLs are microfluidic devices built using laminating materials and a computer-guided craft cutter. Their robustness is comparable to standard PDMS/glass devices in many respects, yet their simplicity makes them ideal for use in a wide range of research laboratories and classrooms at the high school and college level.

PETLs are microfluidic devices built using laminating materials and a computer-guided craft cutter. Their robustness is comparable to standard PDMS/glass devices in many respects, yet their simplicity makes them ideal for use in a wide range of research laboratories and classrooms at the high school and college level.

  • BIOL 107 - Microbes & Disease
  • BIOL 199 - Philosophy of Science
  • BIOL 214 - Microbiology
  • BIOL 311 - Cell Biology
  • BIOL 330 - Advanced Cell Culture and Bioengineering
  • BIOL 357 - Nanobiology
  • BIOL 418 - Immunology

Research

Trained as an immunologist, Dr. Ontiveros is interested in a multidisciplinary approach that blends his expertise with concepts and tools from the fields of bioengineering, cell biology, microbiology, and remote sensing.

There are currently four lines of research in his laboratory:

  • Use of lipid-based nanoparticles to understand the molecular basis of inflammation and to explore novel ways in which drug delivery and vaccination can become more effective.
  • Building of a microbial flora database to enable the detection and prediction of bacterial populations in bodies of fresh water using satellite imagery.
  • Development of a low cost approach to 3D printing of biocompatible hydrogel scaffolds for tissue and organ construction.
  • Educational and research uses of film-based ultra thin microfluidic devices (PETLs) developed in the laboratory.

Recent Publications

  • Implementation and assessment of student-made microfluidic devices in the general chemistry laboratory. Kermin Martinez Hernandez, Nahyr Rovira Figueroa and Fernando Ontiveros. J Nanoeducation. 2016 Dec; 8 (2): 84-113.
  • The semen enhancer of viral infection (SEVI) binds bacteria, enhances bacterial phagocytosis by macrophages, and can protect against a vaginal infection by a sexually transmitted bacterial disease. David Easterhoff*, Fernando Ontiveros*, Lauren R Brooks, Yoel Kim, Brittany Ross, Joanna S. Olsen, Changyong Feng, Dwight J. Hardy, Paul M. Dunman and Stephen Dewhurst. Antimicrob Agents Chemother. 2013 Jun; 57(6): 2443-50.
  • Transient hypercapnia reveals and underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cgmp signaling and normalization by inhibition of phosphodiesterase-5. Jharon Silva, Oksana Polesskaya, Walter Knight, Johnny Ting Zheng, Megan Granger, Tenee Lopez, Fernando Ontiveros, Changyong Feng, Chen Yan, Karl Kasischke and Stephen Dewhurst. J Neuroinflammation. 2012 Nov; 9(1): 253.
  • Il-1 generated subsequent to radiation-induced tissue injury contributes to the pathogenesis of radiodermatitis. Matthew Janko, Fernando Ontiveros, Thomas J. Fitzgerald, A. Deng, Maria DeCicco and Kenneth L. Rock. Radiat. Res. 2012 Sep; 178(3): 166-72.
  • Type-I IFN supports primary CD8+ T cell responses to peptide-pulsed dendritic cells in the absence of CD4+ T cell help Fernando Ontiveros, Elizabeth B. Wilson and Alexandra M. Livingstone. Immunology. 2011 Apr; 132 (4):549-58.
  • The sterile inflammatory response. Kenneth L. Rock, Eicke Latz, Fernando Ontiveros and Hajime Kono. Annu Rev Immunol. 2010 Mar; 28:321-42.
  • Uric acid promotes an acute inflammatory response to sterile cell death in mice. Hajime Kono, Chun-Jen Chen, Fernando Ontiveros and Kenneth L. Rock. J Clin Invest. 2010 Jun 1;120(6):1939-49.

Additional Information